Kamis, 30 September 2010

Magnesium!

I'll get back to Alzheimer's Dementia and fats. But I'm left-handed, and it is more interesting for me to multitask than to stay on one topic in a particularly organized fashion. I have a right-handed accountant for that sort of thing. Ooh, a butterfly fluttered by the window! Pretty!Ahem. Magnesium is another one of those minerals that our ancestors got lots of, but now we don't. Eaton, Eaton,...
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Senin, 27 September 2010

Alzheimer's and Omega 3s

Let's continue on our journey deconstructing and reverse engineering psychiatry from an evolutionary medicine perspective. That is, I assume the correct answer and see how the many pieces fit. There is a danger from this approach - if the main hypothesis is incorrect, I might be wasting a lot of time. But I'm having a bit of fun in the process, and it's quite remarkable just how many connections can...
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Sabtu, 25 September 2010

Your Brain on Omega 3s

Nitty gritty time. I've been touting the benefits of omega 3 fatty acids from the beginning of the blog, but I haven't really gone into exactly what those marine-animal derived PUFAs are doing up there, and why they are so important. Fortunately, one of the papers I'm reading for the Alzheimer's series has an excellent discussion. (1)If you recall, the brain has a heck of a lot of cell membranes,...
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Kamis, 23 September 2010

ADHD, Food Additives, and Histamine

I'll get back to the wild world of Alzheimer's research in a day or two.  My September issue of the Green Journal arrived via USPS this afternoon, and of course this paper caught my eye:"The Role of Histamine Degradation Gene Polymorphisms in Moderating the Effects of Food Additives on Children's ADHD Symptoms."A colleague rolled her eyes at me when I squeaked while reading the title.  But...
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Rabu, 22 September 2010

Over the last two posts I explored the theory that hyperglycemia might be one of the predisposing factors for developing Alzheimer's dementia.  The epidemiological studies looked pretty solid (though we know that a strict reliance on epidemiology can cause us to do ridiculous things, such as eating boneless skinless chicken breasts or, even worse,...
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Minggu, 19 September 2010

Alzheimer's and Hyperglycemia 2

So we know what Gary Taubes thinks.  Since Good Calories, Bad Calories: Fats, Carbs, and the Controversial Science of Diet and Health (Vintage) came out, there has been quite a bit more research into the topic of metabolic syndrome and the risk for Alzheimer's dementia.  I'm going to list some of the papers and the results to show what we're...
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Sabtu, 18 September 2010

Alzheimer's and Hyperglycemia

courtesy wikipediaThe theory that Alzheimer's dementia is in part caused by metabolic syndrome is fairly well known in the paleoblogosphere and literature. I touch upon it now more for the sake of completeness than to try to explore anything new and mind-blowing - at least for the first part of the series. Also, I always learn a bit more about neurobiology...
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Kamis, 16 September 2010

If you recall from Love and Opium, I discussed how borderline personality disorder possibly stems from attachment problems combined with temperamental sensitivity plus opiate receptor issues.  And in other posts, I've discussed the basic idea that excess glutamate is Evil in our poor brains. Well, a new article in the Archives of General Psychiatry brings it all together!  Amazing what happens...
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Selasa, 14 September 2010

Schizophrenia Round-up and Back to School

Today I went back to school.  Every fall, I help teach the introduction to psychiatry class for the second year medical students at my institution.  I work with a small group, teaching basic interviewing and write-up skills.  Today was a large lecture, though, so I got to be in the audience, thumbing through this month's stack of journals while the students were Introduced to Psychiatry.  There...
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Minggu, 12 September 2010

Autism 4 - Inflammation Speculation

Charles Ives (insurance specialist and modern composer) wrote The Alcotts (right click to open in new tab) somewhere around 1911.  It's his most accessible work, as he was one of the first experimenters with polytonal music - you'll hear some, but not too many, of the clashing polytones in this piece.  He composed many melodies from the early 1900s right up until 1927, when one day he came...
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Sabtu, 11 September 2010

Autism and Vitamin D

Vitamin D researcher Dr. John Cannell is all over this one, so I don't need to reinvent the wheel here.  I'll hit the highlights and link his articles for the full discussion.  His 2007 article (thank you, Jamie, still commenting and sending amazing articles and links from a disaster zone!) may be familiar to some of you from the vitamin...
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